Recommended: The random risks of randomised trials

This is an overview of some of the ethical controversies associated with randomization. It includes an interesting story of an early trial by Archie Cochrane that raised a lot of fuss at the time because it was attacking one of the “sacred cows” of medicine.

Harford T. The random risks of randomised trials. Financial Times. http://www.ft.com/intl/cms/s/2/59bb202c-ca7b-11e3-8a31-00144feabdc0.html#axzz30BOFBYb7. Accessed April 28, 2014.