Category Archives: Statistics

PMean: Open source as a budgetary measure

Like a lot of public universities, UMKC is having a lot of financial difficulty. They are asking for advice from faculty members on how to address this budget shortfall. Not being the bashful type, I suggested that we stop paying commercial software vendors and commercial journal publishers and rely instead on open source. Here’s the details of my letter. Continue reading

PMean: Extremely imbalanced multi-center trials

There was some recent discussion of issues with multi-center trials where one center dominates, contributing as much as 94% of all the patients. What does this do to the generalizability of the study. I wanted to summarize these comments here, because it relates to some of the issues I’m looking at right now in accrual models for multi-center trials. Continue reading