I’m attending a great short course on non-inferiority trials and the speaker provided a key reference of historical interest. This reference is the one that got the Statistics community interested in the concept of non-inferiority. The full text is behind a paywall, but you can look at the abstract. A footnote is a paper, Dunnett and Gent 1977, (also trapped behind a paywall) addressed this problem earlier. Continue reading
A nice overview of the problems with shoddy research in genetics testing. It highlights the work of “forensic statistics” of Keith Baggerly and Kevin Coombes. Continue reading
This article outlines a standardized way to describe genetic variants.
If you want to understand the value of genomic medicine, you can learn a lot by reviewing the case of Nicholas Volker, one of the first success stories in this area. Here’s a nice review. Continue reading
This paper advocates something I would call a triple blind, keeping the doctor, the patient, and the statistician who analyzes the data in the dark as to which treatment group is which. This avoids problems where the people analyzing the data will either consciously or subconsciously manipulate the data to get a preferred result. Interesting idea, though it represents an awful amount of work to pull it off. Continue reading
It’s very easy, apparently, to set up your own server to run Shiny apps (Shiny is a web based method for interacting with R code). If you have set up Amazon Web Services, then it is even easier. Here is a detailed account of how to do this. Once I get my own Shiny server going, I will let you know. Continue reading
I really enjoy using RStudio, but one thing about it drives me bats. It seems to use red text for some very innocuous error messages. Continue reading
I might as well recommend something that I wrote. This is a short article in the Amstat News, a monthly newsletter of the American Statistical Association. I talk about all the reasons you wouldn’t want to be an independent consultant and the one big reason why you would–being in control. Continue reading